Team 2021

Team 2019

Principal Investigator

Su Ryon Shin, PhD

Su Ryon Shin is an Assistant Professor and Principal Investigator of Medicine at Brigham and Women’s Hospital, Harvard Medical School. Dr. Shin received a doctoral degree from Hanyang University, South Korea. In November 2010, she joined Prof. Ali Khademhosseini’s group at Brigham and Women’s Hospital, Harvard Medical School, Harvard-MIT Division of Health Sciences and Technologies, and Wyss Institute for Biologically Inspired Engineering as a Postdoctoral Research Fellow. Dr. Shin is an expert in the field of nanomaterials, biomaterials, tissue engineering, electrochemical actuator, biosensor, organ-on-a-chip, and 3D bioprinting.

Contact: shin.lotus@gmail.com; sshin4@bwh.harvard.edu
Office Phone: (617)-768-8320

Early Career Investigator

Shabir Hassan, DSc, Instructor

Shabir is an Early Career Investigator (Instructor of Medicine at Harvard Medical School) in Shin Lab. He completed his bachelor’s in Chemistry, Biology and English from University of Kashmir and his master’s in Biotechnology from University of Pune. After a year of research in molecular biology through LSZGS of UZH/ETH Zurich, he moved to a spectroscopy lab for his Dr. Sc. He used ultrafast laser spectroscopy to study protein folding, aggregation, and photothermal effects in proteins in real time. In 2016, he won the Swiss National Science Foundation (SNSF) fellowship to carry out his research at Harvard Medical School in drug and metabolite delivery applications of novel nanoparticles targeting diseases and other medical conditions. In 2018, he won an Advanced Grant from SNSF to do his collaborative research at Harvard/MIT and University of Twente, Netherlands. His research interests include biomaterials, bioengineering, and biophotonics/imaging. He was awarded BWH and Harvard Medical School’s Award of Excellence for Mentorship in 2019.

Contact: shassan@bwh.harvard.edu

Postdoctoral Research Fellows

Hiroyuki Tetsuka, PhD

Hiroyuki is a researcher of Toyota Motor Engineering & Manufacturing North America, Inc. He obtained his PhD in Engineering in 2006. After working at a National Institute of Advanced Industrial Science and Technology, he joined Toyota Central R&D Labs., Inc. in 2009. His scientific interests are in 2D materials such as silicates, oxides, and graphene nanosheets for use in optical and energy-related devices. In Mar. 2019, he joined the Shin Lab. as a visiting scientist. Now, his interests span multi-disciplinary research which fuses materials science, biological science and engineering.

Contact: htetsuka@bwh.harvard.edu

Takaaki Hatanaka, PhD

Takaaki is a researcher of Toyota Motor Engineering & Manufacturing North America, Inc. He obtained his PhD in Science in 2013 and joined Toyota Central R&D Labs, His research has focused on molecular biology and protein engineering. By using the phage display system, he identified functional proteins/peptides. He also knows how to elucidate the molecular interactions by using Biophysical analysis techniques, such as binding thermodynamics, kinetics and structural analysis (MD simulation and NMR. In March 2021, he joined the Shin Lab. as a visiting scientist. Now, his research interests are origin of life and multi-disciplinary research which fuses bioengineering, optics, materials science.

Contact: htakaaki@bwh.harvard.edu

Myung Chul Lee, PhD

Myung is a postdoctoral fellow in Shin’s lab since Feb 2021. During his master’s course, he performed regenerative medical research using adult stem cells and scaffolds, and developed a device for gene transfection. In his PhD course, he studied targeting cancer therapy for glioblastoma multiforme (brain tumor) using CRISPR based non-viral delivery systems. He is well accomplished and trained in designing new gene/drug delivery carriers, selection of target molecules, in vitro, and in vivo tumor models, and clinical application-specific studies. He has focused on genetic engineering and biological engineering, ultimately aiming for bio-convergence of his research findings into biosystems engineering.

Contact: mlee102@bwh.harvard.edu

Nicole Joy Bassous, PhD

Nicole is a Postdoctoral Fellow in Dr. Su Ryon Shin’s Tissue Engineering and Biomaterials Laboratory at Brigham and Women’s Hospital, Harvard Medical School, HST. Her postdoctoral work postulates the design of artificial tissues that are functionalized to repair or replace damaged organs or organ structures. Originally from New York City, Dr. Bassous attended Rutgers University, where she obtained her Bachelor’s degree in Chemical Engineering, Summa Cum Laude. As an undergraduate, Dr. Bassous became an Aresty Chemistry Fellow in Dr. Wilma K. Olson’s Molecular Biophysics/BioMaPS lab, where she performed bio-computational work addressing the theoretical determination of protein-DNA mechanical properties and morphologies in collaboration with Dr. Tahir I. Yusufaly. Her employment as an intern at VaxInnate, a BioTechnology Vaccine Company, encouraged her passion to pursue graduate research oriented towards the obstruction of disease through an understanding of adaptive immunity, immunology, and microbiology principles. These experiences motivated Dr. Bassous to select biomedical research as a point of interest, and thus, a doctoral program in nanomedicine and biomaterials fabrications at Northeastern University, where her PhD advisor, Dr. Thomas J. Webster, was very instrumental in shaping her awareness for the importance of goodwill and hard work in advancing both science and engineering as interdisciplinary fields. As a PhD researcher at Northeastern University, Dr. Bassous became involved in several independent and collaborative works. The objectives of her PhD entailed the production of multi-functional polymer drug delivery systems, or polymersomes, and heavy metal nanoparticles that concomitantly repressed drug-resistant microbes and ameliorated the secondary syndromes caused by bacteria-host cell interactions, such as mitochondrial dysfunction. In academic-corporate collaborations with national and international research institutions, she has aided in assessing and improving implant and medical scaffolding technologies, especially, for treating musculoskeletal deficiencies (MSDs). Dr. Bassous’ current research goals are to lead in the elaboration of mechanisms for manufacturing viable tissues and organs (tissue engineering applications) or medicinal nanoparticles and drug carrier devices (drug delivery applications); to study the influence of biological, mechanical, and chemical parameters or input materials on disease progression, inflammation, (re)cellularization and tissue function, as enforced by the appropriate assays; and to establish biofunctional products, especially by incorporating concepts in tissue engineering (especially, cardiac), 3-D bioprinting, materials science, drug delivery, cell biology, genetic engineering molecular sensing, immunology, and microbiology.

Contact: nbassous@bwh.harvard.edu

PhD Students

Zahra Rezaei

Zahra is in her fourth year of studies towards a PhD in Chemical Engineering at Sharif University of Technology, Iran. She has previously worked with electrochemical-based micro-biosensors for early detection of cancers. Her interests include developing biosensors, microfluidic devices, organs on a chip and 3D bioprinting. Zahra joined Dr. Shin’s lab in May 2019.

Contact: LinkedIn

Dilara Yilmaz

Dilara is a PhD Research Scholar in Shin Laboratory at Harvard Medical School, Brigham and Women’s Hospital since August 2021. She received her BSc and MSc in Chemical Engineering from Istanbul University, Turkey. Her MSc research was mainly focused on layer-by-layer (LbL) nano structured functional polymeric films and stimuli-responsive systems for drug delivery. She worked in the pharmaceutical industry where she was involved in analytical method development and validation of analytical test methods for oncology medicines as a research and development specialist (R&D Department) for 4 years. Her current research interests are biomaterials, bioengineering, tissue engineering and 3D bioprinting.

Contact: LinkedIn

Weida Zhuang

Weida is a PhD student in orthopedics at Southern Medical University, China. His previous work focused on clinical practices as well as basic research on 3D bioprinting on bone regeneration. Weida joined Shin’s Laboratory at Brigham and Women’s Hospital, Harvard Medical School, in January 2022. His current research involves stem cell organoids for investigating osteogenesis and its application in tissue engineering.

Jihyun Kim

Jihyun is a visiting scholar in Shin Laboratory since March 2022. She is a master & PhD combined course in Electrical & Electronic engineering at Yonsei university in Korea. She has been applying an anti-thrombotic surface on various materials and measuring pH with a FET biosensor. Her current research interests are developing biosensors, medical devices and biomedical engineering.

Master Students

Elisa Doorn

Elisa is a physician-researcher candidate, currently in her final year of the SUMMA (Selective Utrecht Medical Master) Master’s program at the University of Utrecht in the Netherlands. This four-year medical degree prepares students for careers in both clinical medicine as well as research. Elisa obtained a Bachelor’s degree in Veterinary Medicine (cum laude) from the University of Utrecht in 2017, after which she decided to pursue a career in human medicine. She completed two separate Honours programs during the course of her studies and has undertaken medical clerkships with a focus on general surgery and cardiothoracic surgery. Elisa joined the Shin’s Laboratory at Brigham and Women’s Hospital, Harvard Medical School, in January 2022. Her current research involves developing dynamic heart-on-a-chip models in order to study adverse cardiac remodeling, specifically in the context of heart failure. Her research interests include microfluidics, organ-on-a-chip systems, organoids, biomedical engineering and bioprinting.

Contact: LinkedIn

Jiseong Kim

Jiseong is a visiting scholar in Shin’s lab since February 2022. He is a bachelor & master combined course in Dongguk university in Korea. He has cultured embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC) to establish mesenchymal stem cells. Also, he is interested in biological factors like exosome and ECM for investigating differentiation and therapeutic effects of stem cells.

Isa Porsul

Isa joined Shin’s Laboratory in March 2022 as a research trainee. After receiving her bachelors degree in Biomedical Technology from the University of Twente, she started with her master Biomedical Engineering with Bioengineering as the main track. Her interests include microfluidics, tissue engineering, organ-on-a-chip systems, and cell stimulation and differentiation.

Contact: LinkedIn

Undergraduate Students

Mayra Celada Arias

Mayra is a senior year Biotechnology Engineering student with a minor in Molecular Biology at Tecnológico de Monterrey. Her research interests are biomedical engineering, cell and tissue culture, and genetic engineering.

Contact: LinkedIn

Daniela Zavala

Daniela is a senior year Mechatronics Engineering at Tecnológico de Monterrey. She has been in projects using synthetic biology such as iGEM developing a bio sensor. Her fields of interest are Bioprinting, Biosensors and Biomaterials for neural tissue engineering.

Carol Hernández Cantú

Carol is a senior year Biomedical Engineering student with a minor in Neuroscience at Tecnológico de Monterrey. Her fields of interest are, biomaterials for neural tissue engineering, biosensors, and bioprinting.

Contact: LinkedIn

Sebastian Herrera Cruz

Sebastian is in his third year of study towards a bachelor’s in Chemistry and Nanotechnology Engineering at Tecnologico de Monterrey. His interests are in nano-biomaterials for cardiac tissue engineering, synthesis and characterization of biomaterials, cell and tissue culture and biosensors.

Contact: LinkedIn

Ashly Corona Rodriguez

Ashly is currently studying for a BS in Biotechnology Engineering at Tecnologico de Monterrey. Her fields of interest are in Tissue Engineering, Bioprocessing, Bioprinting and Biomedical engineering.

Contact: LinkedIn

Montserrat Pineda

Montse is a senior year Biotechnology Engineering student at Tecnológico de Monterrey, campus Queretaro. She has previously worked understanding diverse molecular receptors involved in renal autoimmune diseases; additionally, cloning and expressing P450 enzymes in E.Coli. Joining Shin Lab in September 2021, her interests include tissue engineering and biomaterials as application for regeneration.

Contact: LinkedIn

Ana Marie Perea

Ana Marie is currently studying for a BS in Biomedical Engineering and a minor in Microtechnologies at Tecnologico de Monterrey. Her fields of interest are in Biomedical Microelectromechanical Systems, Bioprocessing and Molecular, Cellular and Tissue Engineering.

Contact: LinkedIn

Margot Barroso Zuppa

Margot is a senior year medical student at Tecnológico de Monterrey. She did her medical clerkships at ABC Medical Center and she has worked in research in genetics and neuroscience. Her interests include neurosurgery and learning new therapies involving nanotechnology and biomaterials.

Contact: LinkedIn

Fatima Tourk

Fatima graduated from George Washington University with a BS in biomedical engineering. She has previously worked on active orthotics with mechanical sensors as well as soft robotics projects. Her interests include prosthetics and orthotics, assistive robotics, and medical devices.

Contact: LinkedIn

Berenice Ferruzca

Berenice is a senior year biotechnology engineering student with a minor in Bioprocess at Tecnológico de Monterrey. She has previously worked characterizing P. americana sun-blotch viroid and sequencing its RNA. Her fields of interests are biomaterials, tissue culture and genetic engineering.